There’s something truly magical about hitting the open road with nothing but a map, a playlist, and a spirit of adventure. The United States is packed with breathtaking landscapes, vibrant cities, quirky small towns, and endless opportunities for exploration. Whether you’re chasing coastal sunsets, desert vistas, or mountain views, there’s a road trip route that promises unforgettable memories. Discover some epic U.S. road trips you absolutely have to take at least once.
1. Pacific Coast Highway (California)
Route: San Francisco to San Diego
Distance: ~600 miles
The Pacific Coast Highway (PCH) also known as Highway 1, offers one of the most scenic coastal drives in the world. You’ll cruise past rugged cliffs, charming seaside towns, iconic beaches, and sweeping ocean views.
Highlights:
- Big Sur’s dramatic coastline
- Bixby Creek Bridge
- Monterey’s historic Cannery Row
- Santa Barbara’s Spanish architecture
Pro Tip:
Take your time and stop often, this drive is all about soaking in the views.
2. Route 66 (Illinois to California)
Route: Chicago to Santa Monica
Distance: ~2,400 miles
Known as the “Main Street of America,” historic Route 66 captures the nostalgic spirit of cross-country travel. While much of the original road has been replaced, you can still experience stretches filled with vintage diners, classic motels, and quirky roadside attractions.
Highlights:
- Cadillac Ranch in Texas
- Petrified Forest National Park in Arizona
- Historic Downtown Albuquerque
- Santa Monica Pier in California
Pro Tip:
Bring a guidebook to find the best preserved parts of the old route.
3. Blue Ridge Parkway (Virginia to North Carolina)
Route: Shenandoah National Park to Great Smoky Mountains National Park
Distance: ~469 miles
The Blue Ridge Parkway winds through the Appalachian Highlands, offering some of the most beautiful mountain scenery in the U.S. It’s especially breathtaking in the fall when the leaves turn brilliant shades of red, gold, and orange.
Highlights:
- Skyline Drive
- Grandfather Mountain
- Linville Falls
- Mount Mitchell, the highest peak east of the Mississippi
Pro Tip:
There are no billboards or commercial developments along the parkway — perfect for uninterrupted nature immersion.
4. Great River Road (Minnesota to Louisiana)
Route: Along the Mississippi River
Distance: ~3,000 miles
Following the course of the mighty Mississippi River, the Great River Road takes you through ten states and a wide variety of cultures, landscapes, and historical sites.
Highlights:
- Itasca State Park, the river’s source
- Historic river towns like Hannibal, Missouri (Mark Twain’s hometown)
- Blues Trail markers in Mississippi
- New Orleans’ French Quarter
Pro Tip:
Stop at small towns along the way to experience authentic local culture and cuisine.
5. Utah’s Mighty 5 National Parks
Route: Zion to Arches National Park
Distance: ~380 miles
For jaw-dropping desert landscapes and otherworldly rock formations, nothing beats a road trip through Utah’s five iconic national parks: Zion, Bryce Canyon, Capitol Reef, Canyonlands, and Arches.
Highlights:
- Angel’s Landing hike in Zion
- Hoodoos of Bryce Canyon
- Delicate Arch in Arches
- Scenic drives through Canyonlands and Capitol Reef
Pro Tip:
Plan at least a week for this trip — each park deserves at least a full day.
6. Florida Keys Overseas Highway
Route: Miami to Key West
Distance: ~113 miles
The Overseas Highway is a tropical dream, featuring miles of roadway surrounded by the turquoise waters of the Atlantic Ocean and Gulf of Mexico. It’s a sun-soaked, island-hopping journey that feels worlds away from the mainland.
Highlights:
- Seven Mile Bridge
- Key Largo’s coral reefs
- Key West’s lively Duval Street
Pro Tip:
Take a detour for snorkeling or diving in John Pennekamp Coral Reef State Park.
Hit the Road and Make Memories
A road trip is more than a way to get from point A to point B, it’s an adventure filled with unexpected moments, incredible scenery, and the freedom to explore at your own pace. Whether you choose a coastal cruise, a desert trek, or a mountain journey, these epic U.S. road trips offer experiences you’ll never forget.
So fill up the tank, queue up your favorite playlist, and get ready for the journey of a lifetime.